SINGLE-CELL RESPONSE ANALYSIS
Lead Identification & Optimization
How is QuRIE-seq applied (approach and technology)?
QuRIE-seq
It analyzes genetic perturbations alongside protein and phosphoprotein changes to optimize lead candidates.
It captures immune responses and therapeutic action, offering a more detailed view than traditional methods like CRISPR screens.
Particularly valuable for refining cell therapies and immunotherapies, where protein signaling plays a key role.
Our single-cell response technology impact
on lead identification & optimization:
Optimized Leads
Provides insights into how genetic changes affect mRNA, protein, and phosphoprotein levels to optimize lead candidates.
Immunotherapy Refinement
Helps optimize immune therapies by analyzing immune cell responses at multiple molecular levels
Off-Target Effect Detection
Identifies potential off-target effects early, improving the safety and efficacy of therapeutic candidates.