SINGLE-CELL RESPONSE ANALYSIS
Target Identification & Validation
How is QuRIE-seq applied (approach and technology)?
QuRIE-seq
It it integrates mRNA, protein, and phosphoprotein data to pinpoint therapeutic targets at single-cell resolution.
By comparing diseased and healthy tissues, it uncovers disease-associated cell populations and validates drug targets.
It also enables deeper immune profiling, surpassing traditional immune profiling technologies.
Expected outcomes/results from phase collaboration:
Target Identification
Identifies specific therapeutic targets by capturing mRNA, protein, and phosphoprotein data.
Enhanced Target Validation
Provides a more comprehensive validation by including post-translational modifications and protein interactions.
Improved Immune Profiling
Offers deeper insights into immune responses, crucial for immunotherapy development.