Decoding cellular response... one cell at a time

Complexity of disease biology

Biology operates at the level of molecular networks. Disruption in cell signaling networks is one of the hallmarks of cancer and plays a crucial role in the development and progression of the disease. The development of cancer involves many signaling pathways, regulating cell growth and survival, DNA repair, proliferation, and differentiation, etc. with many (un)known crossovers. These pathways are formed by dozen(s) of proteins on average.