Complexity of disease biology
Biology operates at the level of molecular networks. Disruption in cell signaling networks is one of the hallmarks
of cancer and plays a crucial role in the development and progression of the disease. The development of cancer
involves many signaling pathways, regulating cell growth and survival, DNA repair, proliferation, and
differentiation, etc. with many (un)known crossovers. These pathways are formed by dozen(s) of proteins on
average.